This is not an ink for applying with Copic markers. It is more like gouache or a correction fluid. It can be applied with a brush. Copic Opaque White Pigment is a water-based pigment. It is used mostly for highlight effects, but can also be used for covering mistakes. Opaque white wonÃ†t bleed into the base color, giving sharp line definition. It can be used on permanent ink surfaces as well as with watercolors, colored pencils and paints.